TRT and Sexual Function - Endocrinological Control
People are asking...
I've been on TRT for 1.5 years and have not been able to figure out why it has caused ED. Estrogen is where it should be. I'm not on excess T. Not on ...
The melanocortin receptor pathway is a relatively newly discovered mechanism for both erectile function and libido. It is entirely separate from traditional hormonal pathways previously thought to be ... See Full Answer
No libido increase after starting TRT, probably even slight drop due to balls shrinking and no longer needing regular emptying. Of course I'm going to...
Most instances of low libido are not hormonal. Most low libido is emotional/paychological, stress induced, due to sleep apnea, or relationship Issues. If TRT never improved your libido at all, then th... See Full Answer
38 with hormonal issues and it's attendant symptoms and effect since adolescence. Completely bald by 23, finger nails and pubic hair takes a very long...
Fatigue, confidence, libido, motivation, and erectile function are all things that improve on TRT. Head hair & likely nail growth speed is typically not improved with TRT. Body hair for most men tends... See Full Answer
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At AlphaMD, we're here to help. Feel free to ask us any question you would like about TRT, medical weightloss, ED, or other topics related to men's health. Or take a moment to browse through our past questions.
Introduction
Several hormones and neurotransmitters orchestrate men’s sexual response, including the appetitive (sexual desire) and consummative (arousal and penile erection) phases.
Aim
To provide an overview and recommendations regarding endocrinologic control of sexual desire and arousal and erection and their disturbances.
Methods
Medical literature was reviewed by the subcommittee of the International Consultation of Sexual Medicine, followed by extensive internal discussion, and then public presentation and discussion with other experts. The role of pituitary (prolactin, oxytocin, growth hormone, and α-melanocyte-stimulating hormone), thyroid, and testicular hormones was scrutinized and discussed.
Main Outcome Measures
Recommendations were based on grading of evidence-based medical literature, followed by interactive discussion.
Results
Testosterone has a primary role in controlling and synchronizing male sexual desire and arousal, acting at multiple levels. Accordingly, meta-analysis indicates that testosterone therapy for hypogonadal individuals can improve low desire and erectile dysfunction. Hyperprolactinemia is associated with low desire that can be successfully corrected by appropriate treatments. Oxytocin and α-melanocyte-stimulating hormone are important in eliciting sexual arousal; however, use of these peptides, or their analogs, for stimulating sexual arousal is still under investigation. Evaluation and treatment of other endocrine disorders are suggested only in selected cases.
Conclusion
Endocrine abnormalities are common in patients with sexual dysfunction. Their identification and treatment is strongly encouraged in disturbances of sexual desire and arousal.
https://www.sciencedirect.com/science/article/abs/pii/S1743609516000849
Have a question? Ask us.
At AlphaMD, we're here to help. Feel free to ask us any question you would like about TRT, medical weightloss, ED, or other topics related to men's health. Or take a moment to browse through our past questions.
People are asking...
I've been on TRT for 1.5 years and have not been able to figure out why it has caused ED. Estrogen is where it should be. I'm not on excess T. Not on ...
The melanocortin receptor pathway is a relatively newly discovered mechanism for both erectile function and libido. It is entirely separate from traditional hormonal pathways previously thought to be ... See Full Answer
No libido increase after starting TRT, probably even slight drop due to balls shrinking and no longer needing regular emptying. Of course I'm going to...
Most instances of low libido are not hormonal. Most low libido is emotional/paychological, stress induced, due to sleep apnea, or relationship Issues. If TRT never improved your libido at all, then th... See Full Answer
38 with hormonal issues and it's attendant symptoms and effect since adolescence. Completely bald by 23, finger nails and pubic hair takes a very long...
Fatigue, confidence, libido, motivation, and erectile function are all things that improve on TRT. Head hair & likely nail growth speed is typically not improved with TRT. Body hair for most men tends... See Full Answer
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