Human Chorionic Gonadotropin (hCG)
Maintain Fertility, Optimize Hormone Balance, and Support Testicular Health
Human Chorionic Gonadotropin (hCG) plays a crucial role for men undergoing Testosterone Replacement Therapy (TRT) by helping maintain fertility, preventing testicular shrinkage, and supporting natural hormone production. While TRT effectively boosts testosterone levels, it can also suppress the body's own production of testosterone, leading to reduced sperm production and testicular atrophy over time. This is where hCG comes in.
How hCG Works with TRT
hCG mimics Luteinizing Hormone (LH)—the hormone responsible for signaling the testes to produce testosterone. Since TRT suppresses LH production, hCG can help counteract some of the unwanted side effects of TRT by stimulating the testes directly.
Key benefits include:
✅ Maintains Natural Testosterone Production – Even while on TRT, hCG can keep your body's natural testosterone production from shutting down completely.
✅ Supports Fertility – If you want to maintain or restore sperm production while on TRT, hCG is often essential.
✅ Prevents Testicular Shrinkage – Many men experience testicular atrophy on TRT due to the suppression of LH. hCG helps preserve testicular size and function.
✅ May Improve Mood and Libido – Some men report feeling better overall when using hCG alongside TRT, likely due to a more balanced hormonal environment.
Who Should Use hCG?
hCG is commonly recommended for men on TRT who:
Want to maintain fertility and sperm production
Are concerned about
testicular shrinkage
or discomfort
Prefer to support
natural testosterone production
while on TRT
Experience
low energy, mood swings, or libido issues
despite being on TRT
How Is hCG Administered?
hCG is typically injected subcutaneously (under the skin) a few times per week. Dosage varies based on individual needs and is best determined by a healthcare provider who specializes in hormone therapy.
Is hCG Right for You?
If you're on TRT and want to preserve fertility, maintain testicular function, or optimize hormone balance, hCG could be an essential part of your protocol. Talk to your provider about whether adding hCG to your regimen is the right move for your health goals.
Pricing
$300 /per 10,000 IU*
*This price is typical. The supply duration can be variable based on dosing schedule. Typically last 6-20 weeks.
Dosage
For Hormonal Support on TRT
Starting Dose:
500 to 1,000 IU injected subcutaneously
2-3 times per week
Maintenance:
Adjusted based on response, as determined by your healthcare provider
This helps maintain testicular function and supports natural testosterone production while on TRT.
For Fertility Support While on TRT
Dosage Range:
1,000 to 2,000 IU
2-3 times per week
Purpose:
Stimulates sperm production and supports fertility in men undergoing TRT
If fertility is a priority, hCG is often combined with Clomid or FSH (follicle-stimulating hormone) to optimize sperm production.
For Medically Supervised Weight Management
Dosage Range:
125 to 250 IU
daily
Purpose:
Sometimes used in weight-loss programs to assist in
fat metabolism
and
muscle preservation
hCG for weight loss should always be used under medical supervision, as its effectiveness remains debated in clinical research.
Important Considerations
Always follow the dosage and schedule
prescribed by your provider.
Regular monitoring
is crucial to assess hormone levels and adjust treatment as needed.
If you experience
side effects or changes
, consult your healthcare provider immediately.
Using hCG alongside TRT can help optimize your hormonal health, maintain fertility, and improve overall well-being. Always work with a knowledgeable provider to tailor the protocol to your specific needs.
Side Effects
While hCG is generally safe when used correctly, some men may experience mild side effects. These can include:
Headaches
Fatigue
Irritability or mood swings
Swelling or tenderness at the injection site
Increased estrogen-related symptoms
(such as mild water retention or sensitivity in the chest area)
Rare but Serious Reactions
In rare cases, some individuals may experience allergic reactions, including:
Skin rashes
Difficulty breathing
If you notice any severe side effects, it's critical to consult your healthcare provider immediately. Regular monitoring and adjusting your dosage as needed can help minimize potential risks.
By using hCG under medical supervision, men on TRT can safely maintain testicular function, optimize hormone balance, and support fertility with minimal side effects.
*This price is typical. The supply duration can be variable based on dosing schedule. Typically last 6-20 weeks.
Benefits
- Maintains Natural Testosterone Production
- Preserves Fertility
- Prevents Testicular Shrinkage
- Supports Libido & Sexual Function
- Balances Estrogen Levels
- Enhances Mood & Well-Being
- Supports Natural Hormonal Regulation
- May Improve Semen Volume & Quality
- Helps with Post-TRT Recovery
People are asking...
Are there any studies about TRT affecting sperm quality? I know about motility and sperm count. I mean specifically like denaturing of the sperm quali...
Testosterone does not cause birth defects. Remember what you are injecting is the same substance that has been coursing through your body every single day since birth, testosterone. hCG also does not ... See Full Answer
What are your thoughts on HCG along with TRT? 41 yo started trt about 6 months ago, and considering HGC. What are some advantages, and disadvantages? ...
Pros: Maintain what testicular function you had prior to starting TRT Maintain fertility Maintain the steroid hormone cascade with ample pregnenolone (which has various subtle positive effects) Cons: ... See Full Answer
Does HCG effectively mean I would still produce my own T as well as gain T naturally as I take TRT? Say for example, im on TRT and HCG, I’m going to t...
Not quite. A good way to think about it is that the main purpose & effect of HCG is to "prime" the testes for production, which will do a good job of keeping spermatic production up during TRT or reco... See Full Answer
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