Semaglutide Weight Loss Dosage Chart: A Comprehensive Guide

Author: AlphaMD
Semaglutide Weight Loss Dosage Chart: A Comprehensive Guide

Semaglutide has become a popular choice for medical weight loss, offering hope to individuals struggling with obesity or overweight-related health conditions. While originally developed as a treatment for type 2 diabetes, semaglutide has demonstrated significant benefits for weight management. This guide explains the dosage progression for semaglutide used in weight loss therapy, helping patients and practitioners better understand its use.

Understanding Semaglutide for Weight Loss

Semaglutide is a GLP-1 receptor agonist, a class of medications that mimic a hormone in the body called glucagon-like peptide-1. GLP-1 slows digestion, reduces appetite, and regulates blood sugar levels—all of which contribute to weight loss when combined with healthy lifestyle changes.

Unlike brand-name options like Ozempic or Wegovy, AlphaMD offers compounded semaglutide for medical weight loss. This provides patients with a cost-effective and customized approach to their weight management journey.


The Semaglutide Weight Loss Dosage Chart

A gradual titration schedule is essential for semaglutide therapy to minimize side effects such as nausea, vomiting, and gastrointestinal discomfort. Here’s a general dosage progression for weight loss:

Weeks

Dosage

Frequency

1-4

0.25 mg

Once weekly

5-8

0.5 mg

Once weekly

9-12

1.0 mg

Once weekly

13-16

1.7 mg

Once weekly

17+

2.4 mg (Target)

Once weekly


Why the Gradual Titration Schedule?

The stepwise increase in dosage is designed to help the body adapt to the medication. Starting with a low dose reduces the risk of side effects, particularly nausea, which is the most commonly reported issue. Patients reach the target maintenance dose of 2.4 mg by week 17, although the timeline may vary depending on individual tolerability.


How Semaglutide is Administered

Semaglutide is delivered via a once-weekly subcutaneous injection. The injection site can be in the abdomen, thigh, or upper arm. Patients should rotate injection sites to avoid irritation. If a dose is missed, it should be taken as soon as possible within five days. If more than five days have passed, skip the missed dose and continue with the next scheduled dose.


Safety Considerations

While semaglutide is highly effective for weight loss, it is not suitable for everyone. Patients should consult with a qualified medical provider to determine if semaglutide is appropriate for their needs. Individuals with a history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) should not use this medication.

Other common side effects include:

  • Nausea

  • Diarrhea

  • Constipation

  • Fatigue

In rare cases, more serious side effects like pancreatitis or gallbladder issues may occur. Patients experiencing severe side effects should contact their healthcare provider immediately.


Compounded Semaglutide from AlphaMD

At AlphaMD, we offer compounded semaglutide as part of our medical weight loss program. Compounded medications are custom-made by licensed pharmacists, providing an alternative to brand-name drugs. Patients benefit from a tailored dosage and formulation that aligns with their specific health goals.


The Importance of Lifestyle Changes

While semaglutide is a powerful tool for weight management, it’s most effective when combined with sustainable lifestyle changes. A healthy diet, regular physical activity, and behavioral modifications are essential for long-term success. AlphaMD’s team of healthcare providers works closely with patients to create a comprehensive plan that supports their weight loss journey.


Final Thoughts

Semaglutide has revolutionized weight loss therapy, offering hope to those who have struggled with traditional methods. Understanding the proper dosage progression and adhering to the treatment plan can maximize the benefits of this medication while minimizing side effects.

AlphaMD is committed to providing safe and effective medical weight loss solutions, including compounded semaglutide. If you’re considering semaglutide for weight loss, schedule an online consultation with one of our licensed providers to learn more about your options.

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