Alternatives to Testosterone Replacement: Testosterone Restoration
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Hi im questioning if i could benefit from trt. I'm 34m. 6' tall, 191lbs. in my late 20's i decided to try aas. since coming off my life has been a ro...
So the main questions here, did you feel good on AAS? How long ago was that? Typically with any steroid (Testosterone included, though we tend to not think of it as one) you'll have some natural suppr... See Full Answer
Fitness question: Many men think about starting TRT with their natural T levels in the 200-400 range. How much improvement in the gym would such patie...
In general, men who have levels in those ranges & who are experiencing low Testosterone symptoms will already have difficulty putting on muscle mass, maintaining it, and keeping fat off due to those f... See Full Answer
38 with hormonal issues and it's attendant symptoms and effect since adolescence. Completely bald by 23, finger nails and pubic hair takes a very long...
Fatigue, confidence, libido, motivation, and erectile function are all things that improve on TRT. Head hair & likely nail growth speed is typically not improved with TRT. Body hair for most men tends... See Full Answer
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The European Male Aging Study has demonstrated that the hypogonadism of male aging is predominantly secondary. Theoretically with appropriate stimulation from the pituitary, the aging testis should be able to produce eugonadal levels of testosterone. The strategies for the treatment of late onset hypogonadism (LOH) have focused on replacement with exogenous testosterone versus restoration of endogenous production. The purpose of this article is to review existing peer-reviewed literature supporting the concept of restoration of endogenous testosterone in the treatment of LOH.
In view of the EMAS studies, secondary hypogonadism accounts for over 85% of LOH. Ample evidence exists for a deficiency in GTP stimulation with the older men and the ability of the testes to respond to increased GTP production. We currently have several generic medications that accomplish an increase in GTP and normalization of serum testosterone with a favorable side-effect profile. Though shown to be efficacious and well-tolerated in a number of trials, none of the restorative strategies are FDA approved and caution must be advised in their off-label use. Hopefully, future trials will be undertaken to establish a long-term efficacy and safety restorative therapies. Early clinical trials of the compound enclomiphene are encouraging and hopefully will lead to a change in paradigm from TREP to TRES.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650464/
Have a question? Ask us.
At AlphaMD, we're here to help. Feel free to ask us any question you would like about TRT, medical weightloss, ED, or other topics related to men's health. Or take a moment to browse through our past questions.
People are asking...
Hi im questioning if i could benefit from trt. I'm 34m. 6' tall, 191lbs. in my late 20's i decided to try aas. since coming off my life has been a ro...
So the main questions here, did you feel good on AAS? How long ago was that? Typically with any steroid (Testosterone included, though we tend to not think of it as one) you'll have some natural suppr... See Full Answer
Fitness question: Many men think about starting TRT with their natural T levels in the 200-400 range. How much improvement in the gym would such patie...
In general, men who have levels in those ranges & who are experiencing low Testosterone symptoms will already have difficulty putting on muscle mass, maintaining it, and keeping fat off due to those f... See Full Answer
38 with hormonal issues and it's attendant symptoms and effect since adolescence. Completely bald by 23, finger nails and pubic hair takes a very long...
Fatigue, confidence, libido, motivation, and erectile function are all things that improve on TRT. Head hair & likely nail growth speed is typically not improved with TRT. Body hair for most men tends... See Full Answer
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